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Dana Hu-Lowe Selected Research

5- ((5- fluoro- 2- oxo- 1,2- dihydro- 3H- indol- 3- ylidene)methyl)- N- (2- hydroxy- 3- morpholin- 4- ylpropyl)- 2,4- dimethyl- 1H- pyrrole- 3- carboxamide

11/2011The discovery and development of SU14813, a next-generation multitargeted tyrosine kinase inhibitor for the treatment of human malignancies.
7/2006SU14813: a novel multiple receptor tyrosine kinase inhibitor with potent antiangiogenic and antitumor activity.

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Dana Hu-Lowe Research Topics

Disease

7Neoplasms (Cancer)
01/2018 - 09/2005
1Pathologic Neovascularization
05/2012
1Breast Neoplasms (Breast Cancer)
04/2007
1Neoplasm Metastasis (Metastasis)
07/2006
1Colonic Neoplasms (Colon Cancer)
10/2005
1Carcinoma (Carcinomatosis)
09/2005
1Adenocarcinoma
09/2005

Drug/Important Bio-Agent (IBA)

3Phosphotransferases (Kinase)IBA
04/2007 - 09/2005
3Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
04/2007 - 09/2005
3Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
04/2007 - 09/2005
25- ((5- fluoro- 2- oxo- 1,2- dihydro- 3H- indol- 3- ylidene)methyl)- N- (2- hydroxy- 3- morpholin- 4- ylpropyl)- 2,4- dimethyl- 1H- pyrrole- 3- carboxamideIBA
11/2011 - 07/2006
2Tyrosine Kinase InhibitorsIBA
11/2011 - 10/2005
1ARS-1620IBA
01/2018
1Activin Receptors (Activin Receptor)IBA
05/2012
1Transforming Growth Factors (Transforming Growth Factor)IBA
05/2012
1EndoglinIBA
05/2012
1Axitinib (AG 013736)IBA
04/2007
1Tyrosine (L-Tyrosine)FDA Link
04/2007
1Biomarkers (Surrogate Marker)IBA
04/2007
1fms-Like Tyrosine Kinase 3IBA
07/2006
1LigandsIBA
07/2006
1Docetaxel (Taxotere)FDA Link
07/2006
1Proteins (Proteins, Gene)FDA Link
07/2006
1Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA
07/2006
1Proto-Oncogene Proteins c-kit (Proto-Oncogene Protein c-kit)IBA
07/2006
1Platelet-Derived Growth Factor beta Receptor (Receptor, Platelet Derived Growth Factor beta)IBA
07/2006
1Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA
07/2006
1tyrosine receptor (receptor, tyrosine)IBA
07/2006
1Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
10/2005
1GadoliniumIBA
10/2005
1Contrast MediaIBA
10/2005
1Monophenol Monooxygenase (Tyrosinase)IBA
09/2005
1AG 013925IBA
09/2005
1Pharmaceutical PreparationsIBA
09/2005

Therapy/Procedure

4Therapeutics
05/2012 - 09/2005